Biophotonics Imaging Laboratory

Home

 

 

BIOPHOTONICS IMAGING LABORATORY

Imaging Life with Light, not Labels

Led by Prof. Stephen Boppart, the Biophotonics Imaging Laboratory is dedicated to developing novel label-free optical imaging technologies and translating these into clinical applications and for biological discovery.
Biophotonics is an exciting field that investigates fundamental principles and develops new optical technology for the interaction of light or photons with biological organisms, tissues, cells, and molecules. 

Recent Journal Covers

Publications | 2024
PDF | PubMed

Compact simultaneous label-free autofluorescence multi-harmonic microscopy for user-friendly photodamage-monitored imaging

Publications | 2023
PDF | PubMed

Weakly supervised identification of microscopic human breast cancer-related optical signatures from normal-appearing breast tissue

Publications | 2022
PDF | PubMed

Computational photon counting using multi-threshold peak detection for fast fluorescence lifetime imaging microscopy

Publications | 2021
PDF | PubMed

Longitudinal monitoring of cell metabolism in biopharmaceutical production using label-free fluorescence lifetime imaging microscopy (FLIM)

BIL in the News

Load more news

BIL Announcements

  • Congratulations Lilian for receiving the Thomas and Margaret Huang Graduate Fellowship!
  • Congratulations Kevin for Receiving the T32 Predoctoral Toxicology Training Fellowship
  • Congratulations Alejandro for receiving the Beckman Institute Postdoctoral Fellowship
  • Congratulations Janet and Lilian for winning SPIE PW Awards!
  • Professor Boppart will chair the Chancellor's Health Innovation Visioning Committee
  • BIL will have 19 oral presentations SPIE Photonics West in 2023!

    • See previous announcements

    Welcome to our photo gallery! We cherish every image we take through our awesome microscopes, every figure that we make, and every photo that we take. We highlight a few of them here.

    Check out our science-related art and illustrations here!

    View Full Image

    High-throughput NAD(P)H two-photon fluorescence lifetime imaging microscopy mosaic of a rat testis specimen acquired in under 5 min. Bower AJ, Li J, Chaney EJ, Marjanovic M, Spillman DR, Boppart SA. High-speed imaging of transient metabolic dynamics using two-photon fluorescence lifetime imaging microscopy. Optica 5:2190-1296. 2018. 

    View Full Image

    BIL attending Prof. Boppart's investiture as Grainger Distinguished Chain in Engineering, April 2022. 

    View Full Image

    Simultaneous Label-free Multiharmonic Autofluorescence (SLAM) microscopy image.  You S, Barkalifa R, Chaney EJ, Tu H, Park J, Sorrells JE, Sun Y, Liu YZ, Yang L, Chen DZ, Marjanovic M, Sinha S, Boppart SA. Label-free visualization and characterization of extracellular vesicles in breast cancer. PNAS, 116(48):24012-24018. 2019. 

    View Full Image

    Propagation of a Gaussian beam through scattering media! 

    View Full Image

    Guillermo is checking Jenny for the presence of middle-ear effusions using low-coherence interferometry ear probes.

    View Full Image

    COVID can't suppress our holiday spirit!

    View Full Image

    What does the fox say? Photon photon photon. (Origami by Edita Aksamitiene)

    View Full Image

    Can you even spot the ball in this picture?

    Captured @ BIL Farewell picnic

    View Full Image

    Proceedings of BIL second annual camping trip in 10 years!

    View Full Image

    OCT oral cavity imaging on healthy volunteers. Won J, Huang P-C, Spillman DR, Chaney EJ, Wilberg A, Adam R, Klukowska M, Barkalifa R, Boppart SA. Handheld optical coherence tomography for clinical assessment of dental plaque and gingiva. Journal of Biomedical Optics, 25:116011, 2020. 

    View Full Image

    This is us!

    View Full Image

    Janet and Prabuddha see Elisabeth's poster at ISRS 2019. 

    View Full Image

    Keeping the team together even if circumstances keep us apart!

    View Full Image

    In vivo imaging of magnetomotive-force-induced hypothermia using optical coherence tomography and elastography!

    View Full Image

    Working with multiphoton microscopy leads you to have a love–hate relationship with photons! 

    View Full Image