Skin Imaging

Biomechanical Response of Human Skin

The biomechanical response and viscoelastic properties of human skin provide useful information in diagnosing skin pathologies. However, the examination higly relies on the visual inspection and palpation, and there is currently no standard medical device that non-invasively evaluates biomechanical properties of skin. From in vivo skin indentation experiment, we examine the biomechanical response of human skin using OCT system and compared between adults and infants. The polymer indentor is placed onto the skin for 3 minutes on forearm (adults) and thigh (thigh). As soon as the indentor is removed from the skin, OCT system is employed to observe the biomechanical resposnse of the skin as it recovers to the original state. 

     

Demonstration of the skin indentation experiment (left) and OCT images of before and after compression of the skin (right). 

 

Time-lapse OCT images of skin position and structures as the skin recovers to the original state (bottom). 

Reference

Huang P-C, Pande P, Shelton RL, Joa F, Moore D, Gillman E, Kidd K, Nolan RM, Odio M, Carr A, Boppart SA. Quantitative characterization of mechanically indented in vivo human skin in adults and infants using optical coherence tomography. J Biomed Opt. 22(3):034001-034001 2017.  PubMed Abstract PDF