Optical coherence tomography (OCT) is an emerging high-resolution biomedical imaging technology that can perform cellular-level imaging in highly scattering tissue. OCT performs optical ranging in tissue and is analogous to ultrasound except reflections of near-infrared light are detected rather than sound.

CARS is a nonlinear, four-wave mixing process that allows molecules to be identified by their vibrational resonances.

Multi-photon microscopy (MPM) has become a well established optical imaging technique since its first exploitation more than a decade ago. Our optical system configuration extends the capabilities for MPM. MPM is based on the detection of the fluorescence or harmonic-generation signals emitted by endogenous or exogenous markers.

Confocal microscopy allows one to build a three dimensional image of fluorescence based on structure and function.

Optical properties imaging takes advantage of changes in the index of refraction of materials to create high-resolution, highly sensitive, and spatially accurate images of a variety of biological and material samples.

Targeted molecular imaging techniques enable novel contrast and therapeutic agents to be localized to tumor cells and tissues with molecular specificity using principles from immunology and tumor cell biology.