Marjanovic M, Boppart SA. The unperturbed picture: Label-free real-time optical monitoring of cells and extracellular vesicles for therapy. Current Opinion in Biomedical Engineering. 24:100414, 2022. 

Iyer R, Renteria CA, Yang L, Sorrells JE, Park J, Sun L, Yu Z, Huang Y, Marjanovic M, Mirica LM, Boppart SA. Tracking the binding of multi-functional fluorescent tags for Alzheimer's disease using quantitative multiphoton microscopy. J Biophotonics, 15: e202200105, 2022.

Yang L, Park J, Chaney EJ, Sorrells JE, Marjanovic M, Phillips H, Spillman DS, Boppart SA. Label-free multimodal nonlinear optical imaging of needle biopsy cores for intraoperative cancer diagnosis. J Biomed Opt., 27(5):056504, 2022.

Park J, Kamerer RL, Marjanovic M, Sorrells JE, You S, Barkalifa R, Selting KA, Boppart SA. Label-free optical redox ratio from urinary extracellular vesicles as a screening biomarker for bladder cancer. Am J Cancer Res, 12(5):2068-2083, 2022.

Iyer RR, Sorrells JE, Yang L, Chaney EJ, Spillman DR, Tibble BE, Renteria CA, Tu H, Zurauskas, Marjanovic M, Boppart SA. Label-free metabolic and structural profiling of dynamic biological samples using multimodal optical microscopy with sensorless adaptive optics. Sci Rep, 12: 3438, 2022.

Mukherjee P, Aksamitiene E, Alex A, Shi J, Bera K, Zhang C, Spillman DR, Marjanovic M, Fazio M, Seth PP, Frazier K, Hood SR, Boppart SA. Differential uptake of antisense oligonucleotides in mouse hepatocytes and macrophages revealed by simultaneous two-photon excited fluorescence and coherent Raman imaging. Nucleic Acid Ther, 32(3):163-176, 2022.

Sternisha SM, Mukherjee P, Alex A, Chaney EJ, Barkalifa R, Wan B, Lee J H, Rico Jimenez J, Zurauskas M, Spillman DR, Sripada SA, Marjanovic M, Arp Z, Galosy SS, Bhanushali DS, Hood SR, Bose S, Boppart, SA. Longitudinal monitoring of cell metabolism in biopharmaceutical production using label-free fluorescence lifetime imaging microscopy (FLIM). Biotechnol J, 16(7): e2000629, 2021.

Sorrells JE, Iyer RR, Yang L, Chaney EJ, Marjanovic M, Tu H, Boppart SA. Single-photon peak event detection (SPEED): a computational method for fast photon counting in fluorescence lifetime imaging microscopy. Opt. Express 29(23), 37759-37775, 2021.

Zhu D, Wang J, Marjanovic M, Chaney EJ, Higham AM, Liu ZG, Gao Z, Boppart SA. Differentiation of breast tissue types for surgical margin assessment using machine learning and polarization-sensitive optical coherence tomography. Biomed Opt Express, 12(5): 2559-2574, 2021.

Wang J, Chaney E, Aksamitiene E, Marjanovic M, Boppart SA. Computational adaptive optics for polarization-sensitive optical coherence tomography. Opt Lett, 46(9): 2071-2074, 2021.

Sorrells J, Martin E, Aksamitiene E, Mukherjee P, Alex A, Chaney E, Marjanovic M, Boppart SA. Label-free characterization of single extracellular vesicles using two-photon fluorescence lifetime imaging microscopy of NAD(P)H. Sci Rep, 11:3308, 2021.

Bower AJ, Renteria C, Li J, Marjanovic M, Barkalifa R, Boppart SA. High-speed label-free two-photon fluorescence and lifetime imaging microscopy of metabolic transients during neuronal activity. Appl Phys Lett, 118(8): 081104, 2021.

Fabelo C, Selmic LE, Huang P-C, Samuelson J, Reagan JK, Kalamaras A, Marjanovic M, Boppart SA. Evaluating optical coherence tomography for surgical margin assessment of canine mammary tumors. Vet Comp Oncol, 19:697-706, 2021.

Park J, Tu H, You S, Sorrels J, Marjanovic M, Boppart SA. Label-free multimodal multiphoton intravital imaging. In: Optical Imaging in Human Disease and Biological Research (eds. Wei X. and Gu B.), Springer Verlag, Singapore, pp. 127-152, 2021.

Wang J, Chaney E, Aksamitiene E, Marjanovic M, Boppart SA. Compressive sensing for polarization-sensitive optical coherence tomography. J Phys D: Appl Phys, 54 (29): 2940052021, 2021.

Yang L, Park J, Marjanovic M, Chaney E, Spillman D, Phillips H, Boppart SA. Intraoperative label-free multimodal nonlinear imaging for point-of-procedure cancer diagnostics. IEEE J Sel Top Quantum Electron - Biophotonics, 4(27): 1-12, 2021.

Li J, Wilson MN, Bower AJ, Marjanovic M, Chaney EJ, Barkalifa R, Boppart SA. Video-rate multimodal multiphoton imaging and three-dimensional characterization of cellular dynamics in wounded skin. J Innov Opt Health Sci, 13(2): 2050007, 2020. (Cover image)

Rico-Jimenez JJ, Lee JH, Alex A, Musaad S, Chaney EJ, Barkalifa R, Olson E, Adams D, Marjanovic M, Arp Z, Boppart SA. Noninvasive monitoring of pharmacodynamics during the skin wound healing process using multimodal optical microscopy. BMJ Open Diabetes Research & Care, 8: 000974, 2020.

Zurauskas M, Barkalifa R, Alex A, Marjanovic M, Spillman D, Mukherjee P, Neitzel Cl, Lee W, Medler J, Arp Z, Cleveland M, Hood S, Boppart SA. Assessing the severity of psoriasis through multivariate analysis of optical images from non-lesional skin. Sci Rep, 10: 9154, 2020.

Kind MC, Zurauskas M, Alex A, Marjanovic M, Mukherjee P, Doan M, Spillman DR, Hood S, Boppart SA. flimview: A software framework to handle, visualize and analyze FLIM data. F1000Research, 9:574, 2020.

Alex A, Chaney E, Zurauskas M, Criley J, Spillman D, Hutchison P, Li J, Marjanovic M, Frey S, Arp Z, Boppart SA. In vivo characterization of minipig skin as a model for dermatological research using multiphoton microscopy. Exp Dermatol, 00:1-8, 2020.

Sun Y, You S, Du X, Spalding A, Liu ZG, Chaney EJ, Spillman DR, Marjanovic M, Tu H, Boppart SA. Real-time three-dimensional histology-like imaging by label-free nonlinear optical microscopy. Quant Imaging Med Surg (QIMS), 10 (11):2177-2190, 2020.

Selmic L, Samuelson J, Reagan J, Mesa K, Driskell E, Li J, Marjanovic M, Boppart SA. Intraoperative imaging of surgical margins of canine soft tissue sarcoma using optical coherence tomography. Vet Comp Oncol, 17(1): 80-88, 2019.

Liu Y, Tu H, You S, Chaney EJ, Marjanovic M, Boppart SA. Label-free molecular profiling for identification of biomarkers in carcinogenesis using multimodal multiphoton imaging. Quant Imaging Med Surg (QIMS), Special Issue on Advanced Optical Imaging in Biomedicine, 9(5): 742-756, 2019. (Invited paper).

Pool M, Marjanovic M. Work in Progress: Introducing bioengineering approaches through healthcare grand challenges. ASEE, ID#27515, 2019.

Lee JH, Rico-Jimenez JJ, Zhang C, Alex A, Chaney EJ, Barkalifa R, Spillman DR, Marjanovic M, Arp Z, Hood SR, Boppart SA. Simultaneous label-free autofluorescence and multi-harmonic imaging reveals in vivo structural and metabolic changes in murine skin. J Biomed Opt, 10(10): 5431-5444, 2019.

You S, Barkalifa R, Chaney EJ, Tu H, Park J, Sun Y, Liu YZ, Yang L, Chen DZ, Marjanovic M, Sinha S, Boppart SA. Label-free visualization and characterization of extracellular vesicles in breast cancer. PNAS, 116(48): 24012-24018, 2019. (Cover image)

You S, Sun Y, Yang L, Park J, Tu H, Marjanovic M, Sinha S, Boppart SA. Real-time intraoperative diagnosis by deep neural network driven multiphoton virtual histology. npj Precision Oncology, 3:33, 2019.

Bower AJ, Sorrells JE, Li J, Marjanovic M, Barkalifa R, Boppart SA. Tracking metabolic dynamics of apoptosis with high-speed two-photon fluorescence lifetime imaging microscopy. Biomed Opt Express, 10 (12): 6408-6421, 2019.

Alex A, Frey S, Angelene H, Neitzel CD, Li J, Bower AJ, Spillman DR Jr, Marjanovic M, Chaney EJ, Medler JL, Lee W, Vasist Johnson LS, Boppart SA, Arp Z. In situ biodistribution and residency of a topical anti-inflammatory using fluorescence lifetime imaging microscopy. Br J Dermatol, 179(6): 1342-1350, 2018.

Marjanovic M, Nguyen FT, Ahmad A, Huang PC, Suslick KS, Boppart SA. Characterization of magnetic nanoparticle-based microspheres for magnetomotive and multimodal imaging. IEEE J Sel Top Quantum Electron - Biophotonics, 25(1): 1-14. 2018.

Bower AJ, Li J, Chaney EJ, Marjanovic M, Spillman DS, Boppart SA. High-speed imaging of transient metabolic dynamics using two-photon fluorescence lifetime imaging microscopy. Optica, 5(10): 1290-1296, 2018. (Cover image)

Sun Y, You S, Tu H, Spillman DR, Chaney EJ, Marjanovic M, Li J, Barkalifa R, Wang J, Higham AM, Luckey NN, Cradock KA, Liu ZG, Boppart SA. Intraoperative visualization of the tumor microenvironment and quantification of extracellular vesicles by label-free nonlinear imaging. Sci Adv, 4(12): eaau5603, 2018.

Wang J, Xu Y, Mesa KJ, South FA, Chaney EJ, Spillman DR, Barkalifa R, Marjanovic M, Carney PS, Higham AM, Liu ZG, Boppart SA. Complementary use of polarization-sensitive and standard OCT metrics for enhanced intraoperative differentiation of breast cancer. J Biomed Opt, 9(12): 6519-6528, 2018.

Li J, Bower AJ, Arp Z, Olson EJ, Holland C, Chaney EJ, Marjanovic M, Pande P, Alex A, Boppart SA. Investigating the healing mechanisms of an angiogenesis-promoting topical treatment for diabetic wounds using multimodal microscopy. J Biophotonics, 11(3), 2018.

Erickson-Bhatt S, Mesa KJ, Marjanovic M, Chaney EJ, Ahmad A, Huang PC, Liu ZG, Cunningham K, Boppart SA. Intraoperative optical coherence tomography of the human thyroid: Feasibility for surgical assessment. Transl Res, 195:13-24, 2018.

You S, Tu H, Chaney EJ, Sun Y, Zhao Y, Bower AJ, Liu Y, Marjanovic M, Sinha S, Pu Y, Boppart SA. Intravital imaging by simultaneous label-free autofluorescence-multiharmonic (SLAM) microscopy. Nat Commun, 9(1): 2125, 2018.

Bower AJ, Marjanovic M, Zhao Y, Li J, Chaney EJ, Boppart SA. Label-free in vivo cellular-level detection and imaging of apoptosis. J Biophotonics, 10(1): 143-150, 2017.

Tu H, Liu Y, Marjanovic M, Chaney EJ, You S, Zhao Y, Boppart SA. Concurrence of extracellular vesicle enrichment and metabolic switch visualized label-free in the tumor microenvironment. Sci Adv, 3(1): e16006752016, 2017.

Mesa KJ, Selmic LE, Pande P, Monroy GL, Reagan J, Samuelson J, Li, J, Marjanovic M, Chaney EJ, Boppart SA. Intraoperative OCT for soft tissue sarcoma margin identification. Lasers Surg Med, 49(3): 240-248, 2017.

Bower AJ, Chidester B, Li J, Zhao Y, Marjanovic M, Chaney EJ, Do MN, Boppart SA. A quantitative framework for the analysis of multimodal optical microscopy images. Quant Imaging Med Surg, 7(1):24-37, 2017.

Bower AJ, Mahmassani Z, Zhao Y, Chaney EJ, Marjanovic M, LEE MK, Graf BW, DeLisio M, Kong H, Boppart MD, Boppart SA. In vivo assessment of engineered skin cell delivery with multimodal optical microscopy. Tissue Eng Part C Methods, 23(7): 434-442, 2017.

You S, Liu Y, Arp Z, Zhao Y, Chaney EJ, Marjanovic M, Boppart SA. Intracellular imaging of docosanol in living cells by coherent anti-Stokes Raman scattering microscopy. J Biomed Opt, 22(7): 070502, 2017.

Kim J, Ahmad A, Li J, Marjanovic M, Chaney EJ, Suslick K, Boppart SA. Intravascular magnetomotive optical coherence tomography of targeted early-stage atherosclerotic changes in ex vivo hyperlipidemic rabbit aortas. J Biophotonics, 9: 109-116, 2016.

Nolan RM, Adie SG, Marjanovic M, Chaney EJ, South FA, Monroy GL, Shemonski ND, Erickson-Bhatt SJ, Shelton RL, Bower AJ, Simpson DG, Cradock KA, Liu G, Ray PS, Boppart SA. Intraoperative optical coherence tomography for assessing human lymph nodes for metastatic cancer. BMC Cancer, 16:144, 2016.

Bower AJ, Zane ZA, Zhao Y, Li J, Chaney EJ, Marjanovic M, Hughes-Earle AR, Boppart SA. Longitudinal in vivo tracking of adverse effects following topical steroid treatment. Exp Dermatol, 25(5): 362-367, 2016.

Huang P-C, Pande P, Ahmad A, Marjanovic M, Spillman DR, Odintsov B, Boppart SA. Magnetomotive optical coherence elastography for magnetic hyperthermia dosimetry based on dynamic tissue biomechanics. (Invited paper) IEEE J Sel Top Quantum Electron, 22(4), 2016.

You S, Tu H, Zhao Y, Liu Y, Chaney E, Marjanovic M, Boppart SA. Raman spectroscopic analysis reveals abnormal fatty acid composition in tumor micro- and macroenvironments in human breast and rat mammary cancer. Sci Rep, 6:32922, 2016.

Tu H, Liu Y, Turchinovich D, Marjanovic M, Lyngso J, Laegsgaard J, Chaney EJ, Zhao Y, You S, Wilson WL, Xu B, Dantus M, Boppart SA. Stain-free histopathology by programmable supercontinuum. Nat Photonics, 10(8):534-540, 2016.

Li J, Pincu Y, Marjanovic M, Bower, A, Chaney EJ, Jensen T, Boppart MD, Boppart SA. In vivo evaluation of adipose- and muscle-derived stem cells as a treatment for nonhealing diabetic wounds using multimodal microscopy. J Biomed Opt, 21(8): 086006, 2016.

South F, Marjanovic M, Boppart SA. Intraoperative optical coherence tomography for cancer surgery. In: Optical Coherence Tomography: Technology and Applications, 2nd Edition (eds. Drexler W and Fujimoto JG), Springer International Publishing, pp. 2393-2412, 2015.

Erickson-Bhatt SJ, Nolan RM, Shemonski ND, Adie SG, Putney J, Darga D, McCormick DT, Cittadine AJ, Zysk AM, Marjanovic M, Chaney EJ, South FA, Cradock KA, Liu ZG, Sundaram M, Ray PS, Boppart SA. Real-time imaging of the resection bed using a handheld probe to reduce incidence of microscopic positive margins in cancer surgery. Cancer Res, 75: 3706-3712, 2015.

Li J, Bower AJ, Vainstein V, Gluzman-Poltorak Z, Chaney EJ, Marjanovic M, Basile LA, Boppart SA. Effect of recombinant interleukin-12 on murine skin regeneration and cell dynamics using in vivo multimodal microscopy. Biomed Opt Express, 6:4277-4287, 2015.

Li J, Dobrucki LW, Marjanovic M, Chaney EJ, Suslick KS, Boppart SA. Enhancement and wavelength-shifted emission of Cerenkov luminescence using multifunctional microspheres. Phys Med Biol, 60: 727-739, 2015.

South FA, Chaney EJ, Marjanovic M, Adie SG, Boppart SA. Differentiation of ex vivo human breast tissue using polarization-sensitive optical coherence tomography. Biomed Opt Exp, 5: 3417-3426, 2014.

Zhao Y, Marjanovic M, Chaney EJ, Graf BW, Mahmassani Z, Boppart MD, Boppart SA. Longitudinal label-free tracking of cell death dynamics in living engineered human skin tissue with a multimodal microscope. Biomed Opt Express, 5: 3699-3716, 2014.

Zhao Y, Adie SG, Tu H, Liu Y, Graf BW, Chaney EJ, Marjanovic M, Boppart SA. Optical parametrically gated microscopy in scattering media. Opt Express, 22: 22547-22560, 2014.

Ahmad A, Kim, J, Shemonski N, Marjanovic M, Boppart SA. Volumetric full-range magnetomotive optical coherence tomography. J Biomed Opt, 19(12): 126001, 2014.

Graf BW, Chaney EJ, Marjanovic M, Adie SG, De Lisio M, Valero MC, Boppart MD, Boppart SA. Long-term time-lapse multimodal intravital imaging of wound healing and bone-marrow-derived cell dynamics in skin. Technology, 1: 8-19, 2013.

Marjanovic M, Tangella K. Biology of a cancer cell. In: Nanobiophotonics (ed. G. Popescu). McGraw-Hill, New York, pp. 3-13, 2010.

Tangella K, Marjanovic M. Tissue pathology: A clinical perspective. In: Nanobiophotonics (ed. G. Popescu). McGraw-Hill, New York, pp.57-78, 2010.

John R, Rezaeipoor R, Adie SG, Chaney EJ, Oldenburg AL, Marjanovic M, Haldar JP, Sutton BP, Boppart SA. In vivo magnetomotive optical molecular imaging using targeted magnetic nanoprobes. PNAS, 107(18): 8085-8090, 2010.